VALIDATION OF ANALYTICAL METHOD BY UV SPECTROPHOTOMETRIC QUANTIFICATION OF GEMFIBROZIL INCORPORATED IN THE MICROEMULSIONS

The present study aims to validate an analytical method by UV spectrophotometric for the quantification of gemfibrozil incorporated into microemulsions. Experimental development constructing a ternary phase diagram identification characterization microemulsions was carried out polarized light microscopy technique. validated according parameters described United State Pharmacopeia (USP) 39 NF34 and International Conference on Harmonization (ICH) (2005), which evaluated linearity, robustness, intra inter day accuracy, specificity limits detection quantification. developed demonstrated linearity with coefficient determination (R2) 0.9898, in addition precision, accuracy robustness each tests values that presented variation less than 5 %. results obtained were favorable, since they comply stipulated USP 39-NF34 (2016) ICH indicating is effective intended purpose.